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KMID : 0861020060210030097
Korea Journal of Herbology
2006 Volume.21 No. 3 p.97 ~ p.102
A Efficacy of Trigonellae Semen On Treatment of Osteporosis In Ovariectomized Rats
Seo Bu-Il

Abstract
Objectives : The present study had been undertaken to investigate the effects of Trigonellae Semen on treatment of osteoporosis in ovariectomized rats.

Methods : In this experiment, the rats were ovariectomized. Rats were administered by water extracts of Trigonellae Semen. The levels of bone mineral density and body weight were measured.

Results : The levels of spinal bone mineral density was significantly increased in comparison with OVX group at 4 and 8 weeks after medication in Trigonellae Semen group. The levels of femoral and fibula-tibial bone mineral density were significantly increased in comparison with OVX group at 4 weeks after medication in Trigonellae Semen group. The levels of body weight was significantly increased in comparison with OVX group at 4 weeks after medication in Trigonellae Semen group.

Conclusion : Reviewing these experimetal results, it appears that Trigonellae Semen have efficacy on treatment of osteeoporosis. And further study should be conducted to illustrate in depth the curing and prevention of osteoporosis.
KEYWORD
Trigonellae Semen, Osteoporosis
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